A novel RARA–SNX15 fusion in PML–RARA-positive acute promyelocytic leukemia with t(11;17;15)(q13;q21...
A novel RARA–SNX15 fusion in PML–RARA-positive acute promyelocytic leukemia with t(11;17;15)(q13;q21.2;q24.1)
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Singapore: Springer Nature Singapore
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Language
English
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Publisher
Singapore: Springer Nature Singapore
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Contents
Acute promyelocytic leukemia (APL) is characterized by a series of
retinoic acid receptor (RAR)
fusion genes that lead to the dysregulation of RAR signaling and onset of APL. PML–RARA is the most common fusion generated from t(15;17)(q24;q21). In addition, the reciprocal fusion
RARA
–
PML
is present in over 80% of t(15;17) APL cas...
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Full title
A novel RARA–SNX15 fusion in PML–RARA-positive acute promyelocytic leukemia with t(11;17;15)(q13;q21.2;q24.1)
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TN_cdi_proquest_journals_2890045608
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2890045608
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ISSN
0925-5710,1865-3774
E-ISSN
1865-3774
DOI
10.1007/s12185-022-03421-w
