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SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2890159747

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling

About this item

Full title

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has caused millions of deaths since emerging in 2019. Innate immune antagonism by lethal CoVs such as SARS-CoV-2 is crucial for optimal replication and pathogenesis. The conserved nonstructural protein 15 (nsp15) endoribonuclease (EndoU) limits activation of double-stranded (ds)RNA-induced...

Alternative Titles

Full title

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2890159747

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2890159747

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.11.15.566945