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AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental...

AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2895908357

AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental stress

About this item

Full title

AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental stress

Publisher

United States: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-12

Language

English

Formats

Publication information

Publisher

United States: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

CD4+FOXP3+ regulatory T (Treg) cells maintain self-tolerance, suppress the immune response to cancer, and protect against tissue injury in the lung and other organs. Treg cells require mitochondrial metabolism to exert their function, but how Treg cells adapt their metabolic programs to sustain and optimize their function during an immune response...

Alternative Titles

Full title

AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental stress

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2895908357

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2895908357

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.11.29.568904