PIEZO2‐dependent rapid pain system in humans and mice
PIEZO2‐dependent rapid pain system in humans and mice
About this item
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Author / Creator
Bouchatta, Otmane , Brodzki, Marek , Manouze, Houria , Carballo, Gabriela B , Kindstrom, Emma , De-Faria, Felipe M , Yu, Huasheng , Kao, Anika R , Thorell, Oumie , Jaquette Liljencrantz , Ng, Kevin Kw , Frangos, Eleni , Ragnemalm, Bengt , Saade, Dimah , Bharucha-Goebel, Diana , Szczot, Ilona , Moore, Warren , Terejko, Katarzyna , Cole, Jonathan , Bonnemann, Carsten , Luo, Wenquin , Mahns, David A , Larsson, Max , Gerling, Gregory J , Marshall, Andrew G , Chesler, Alexander T , Olausson, Hakan , Nagi, Saad S and Szczot, Marcin
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
The PIEZO2 ion channel is critical for transducing light touch into neural signals but is not considered necessary for transducing acute pain in humans. Here, we discovered an exception - a form of mechanical pain evoked by hair pulling. Based on observations in a rare group of individuals with PIEZO2 deficiency syndrome, we demonstrated that hair‐...
Alternative Titles
Full title
PIEZO2‐dependent rapid pain system in humans and mice
Authors, Artists and Contributors
Author / Creator
Brodzki, Marek
Manouze, Houria
Carballo, Gabriela B
Kindstrom, Emma
De-Faria, Felipe M
Yu, Huasheng
Kao, Anika R
Thorell, Oumie
Jaquette Liljencrantz
Ng, Kevin Kw
Frangos, Eleni
Ragnemalm, Bengt
Saade, Dimah
Bharucha-Goebel, Diana
Szczot, Ilona
Moore, Warren
Terejko, Katarzyna
Cole, Jonathan
Bonnemann, Carsten
Luo, Wenquin
Mahns, David A
Larsson, Max
Gerling, Gregory J
Marshall, Andrew G
Chesler, Alexander T
Olausson, Hakan
Nagi, Saad S
Szczot, Marcin
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2896129065
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2896129065
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2023.12.01.569650
How to access this item
https://www.proquest.com/docview/2896129065?pq-origsite=primo&accountid=13902
