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Paracrine effects of the senescence-associated secretory phenotype decrease cancer cell adhesion

Paracrine effects of the senescence-associated secretory phenotype decrease cancer cell adhesion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2896605631

Paracrine effects of the senescence-associated secretory phenotype decrease cancer cell adhesion

About this item

Full title

Paracrine effects of the senescence-associated secretory phenotype decrease cancer cell adhesion

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

High grade serous ovarian cancer (HGSOC) is the most lethal gynecological cancer. Platinum-based therapies such as cisplatin are standard-of-care for HGSOC patients; however, the majority of HGSOCs initially treated with cisplatin will recur with widespread disseminated disease. Cisplatin induces cellular senescence, a stable cell cycle arrest. Alt...

Alternative Titles

Full title

Paracrine effects of the senescence-associated secretory phenotype decrease cancer cell adhesion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2896605631

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2896605631

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.12.02.569652