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An inducible genetic tool for tracking and manipulating specific microglial states in development an...

An inducible genetic tool for tracking and manipulating specific microglial states in development an...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2897262265

An inducible genetic tool for tracking and manipulating specific microglial states in development and disease

About this item

Full title

An inducible genetic tool for tracking and manipulating specific microglial states in development and disease

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Recent single-cell RNA sequencing studies have revealed distinct microglial states in development and disease. These include proliferative region-associated microglia (PAM) in developing white matter and disease-associated microglia (DAM) prevalent in various neurodegenerative conditions. PAM and DAM share a similar core gene signature and other fu...

Alternative Titles

Full title

An inducible genetic tool for tracking and manipulating specific microglial states in development and disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2897262265

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2897262265

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.12.01.569597