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Development of pre-clinical murine models for fibrolamellar hepatocellular carcinoma

Development of pre-clinical murine models for fibrolamellar hepatocellular carcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2899164157

Development of pre-clinical murine models for fibrolamellar hepatocellular carcinoma

About this item

Full title

Development of pre-clinical murine models for fibrolamellar hepatocellular carcinoma

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Fibrolamellar hepatocellular carcinoma (FLC) is a rare form of cancer that affects primarily teenagers and young adults. FLC tumors are nearly always associated with an intrachromosomal deletion resulting in expression of a fusion protein between the chaperone DNAJ1B and the protein kinase PKA. FLC is challenging to study because of its rarity and...

Alternative Titles

Full title

Development of pre-clinical murine models for fibrolamellar hepatocellular carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2899164157

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2899164157

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.12.06.569624