Cholesterol modulates the human FPN1 iron export function in plasma membrane liquid-ordered microdom...
Cholesterol modulates the human FPN1 iron export function in plasma membrane liquid-ordered microdomains
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Ferroportin 1 (FPN1) is the only known mammalian iron efflux transporter. This multi-pass membrane protein, which adopts the Major Facilitator Superfamily fold, is tightly controlled by serum hepcidin to assure maintenance of adequate cellular and systemic iron levels. Earlier studies have shown that cholesterol-lowering drugs can reduce FPN1 expre...
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Cholesterol modulates the human FPN1 iron export function in plasma membrane liquid-ordered microdomains
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TN_cdi_proquest_journals_2901737345
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2901737345
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E-ISSN
2692-8205
DOI
10.1101/2023.12.14.571614
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https://www.proquest.com/docview/2901737345?pq-origsite=primo&accountid=13902
