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Improved bladder cancer antitumor efficacy with a recombinant BCG that releases a STING agonist

Improved bladder cancer antitumor efficacy with a recombinant BCG that releases a STING agonist

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2902166332

Improved bladder cancer antitumor efficacy with a recombinant BCG that releases a STING agonist

About this item

Full title

Improved bladder cancer antitumor efficacy with a recombinant BCG that releases a STING agonist

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Despite the introduction of several new agents for the treatment of bladder cancer (BC), intravesical BCG remains a first line agent for the management of non-muscle invasive bladder cancer. In this study we evaluated the antitumor efficacy in animal models of BC of a recombinant BCG known as BCG-disA-OE that releases the small molecule STING agoni...

Alternative Titles

Full title

Improved bladder cancer antitumor efficacy with a recombinant BCG that releases a STING agonist

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2902166332

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2902166332

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.12.15.571740