Branched-chain keto acids promote an immune-suppressive and neurodegenerative microenvironment in le...
Branched-chain keto acids promote an immune-suppressive and neurodegenerative microenvironment in leptomeningeal disease
About this item
Full title
Author / Creator
Mariam Lotfy Khaled , Ren, Yuan , Kundalia, Ronak , Alhaddad, Hasan , Chen, Zhihua , Wallace, Gerald C , Evernden, Brittany , Ospina, Oscar E , Maclean Hall , Liu, Min , Lancia Nf Darville , Izumi, Victoria , Chen, Y Ann , Pilon-Thomas, Shari , Stewart, Paul Ann , Koomen, John M , Corallo, Salvatore A , Jain, Michael D , Robinson, Timothy J , Locke, Fredrick L , syth, Peter A and Smalley, Inna
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Leptomeningeal disease (LMD) occurs when tumors seed into the leptomeningeal space and cerebrospinal fluid (CSF), leading to severe neurological deterioration and poor survival outcomes. We utilized comprehensive multi-omics analyses of CSF from patients with lymphoma LMD to demonstrate an immunosuppressive cellular microenvironment and identified...
Alternative Titles
Full title
Branched-chain keto acids promote an immune-suppressive and neurodegenerative microenvironment in leptomeningeal disease
Authors, Artists and Contributors
Author / Creator
Ren, Yuan
Kundalia, Ronak
Alhaddad, Hasan
Chen, Zhihua
Wallace, Gerald C
Evernden, Brittany
Ospina, Oscar E
Maclean Hall
Liu, Min
Lancia Nf Darville
Izumi, Victoria
Chen, Y Ann
Pilon-Thomas, Shari
Stewart, Paul Ann
Koomen, John M
Corallo, Salvatore A
Jain, Michael D
Robinson, Timothy J
Locke, Fredrick L
syth, Peter A
Smalley, Inna
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2903106428
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2903106428
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2023.12.18.572239
How to access this item
https://www.proquest.com/docview/2903106428?pq-origsite=primo&accountid=13902