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CDK13 promotes lipid deposition and prostate cancer progression by stimulating NSUN5-mediated m5C mo...

CDK13 promotes lipid deposition and prostate cancer progression by stimulating NSUN5-mediated m5C mo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2904031548

CDK13 promotes lipid deposition and prostate cancer progression by stimulating NSUN5-mediated m5C modification of ACC1 mRNA

About this item

Full title

CDK13 promotes lipid deposition and prostate cancer progression by stimulating NSUN5-mediated m5C modification of ACC1 mRNA

Publisher

London: Nature Publishing Group UK

Journal title

Cell death and differentiation, 2023-12, Vol.30 (12), p.2462-2476

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cyclin-dependent kinases (CDKs) regulate cell cycle progression and the transcription of a number of genes, including lipid metabolism-related genes, and aberrant lipid metabolism is involved in prostate carcinogenesis. Previous studies have shown that CDK13 expression is upregulated and fatty acid synthesis is increased in prostate cancer (PCa). H...

Alternative Titles

Full title

CDK13 promotes lipid deposition and prostate cancer progression by stimulating NSUN5-mediated m5C modification of ACC1 mRNA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2904031548

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2904031548

Other Identifiers

ISSN

1350-9047,1476-5403

E-ISSN

1476-5403

DOI

10.1038/s41418-023-01223-z

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