Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism und...
Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment
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Author / Creator
Raabe, Florian J , Hausruckinger, Anna , Gagliardi, Miriam , Ahmad, Ruhel , Almeida, Valeria , Galinski, Sabrina , Hoffmann, Anke , Weigert, Liesa , Rummel, Christine K , Murek, Vanessa , Trastulla, Lucia , Jimenez-Barron, Laura , Atella, Alessia , Maidl, Susanne , Menegaz, Danusa , Hauger, Barbara , Wagner, Eva-Maria , Gabellini, Nadia , Kauschat, Beate , Riccardo, Sara , Cesana, Marcella , Papiol, Sergi , Sportelli, Vincenza , Rex-Haffner, Monika , Stolte, Sebastian J , Wehr, Michael C , Salcedo, Tatiana Oviedo , Papazova, Irina , Detera-Wadleigh, Sevilla , McMahon, Francis J , Schmitt, Andrea , Falkai, Peter , Hasan, Alkomiet , Cacchiarelli, Davide , Dannlowski, Udo , Nenadić, Igor , Kircher, Tilo , Scheuss, Volker , Eder, Matthias , Binder, Elisabeth B , Spengler, Dietmar , Rossner, Moritz J and Ziller, Michael J
Publisher
United States: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
United States: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Schizophrenia (SCZ) is a genetically heterogenous psychiatric disorder of highly polygenic nature. Correlative evidence from genetic studies indicate that the aggregated effects of distinct genetic risk factor combinations found in each patient converge onto common molecular mechanisms. To prove this on a functional level, we employed a reductionis...
Alternative Titles
Full title
Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment
Authors, Artists and Contributors
Author / Creator
Hausruckinger, Anna
Gagliardi, Miriam
Ahmad, Ruhel
Almeida, Valeria
Galinski, Sabrina
Hoffmann, Anke
Weigert, Liesa
Rummel, Christine K
Murek, Vanessa
Trastulla, Lucia
Jimenez-Barron, Laura
Atella, Alessia
Maidl, Susanne
Menegaz, Danusa
Hauger, Barbara
Wagner, Eva-Maria
Gabellini, Nadia
Kauschat, Beate
Riccardo, Sara
Cesana, Marcella
Papiol, Sergi
Sportelli, Vincenza
Rex-Haffner, Monika
Stolte, Sebastian J
Wehr, Michael C
Salcedo, Tatiana Oviedo
Papazova, Irina
Detera-Wadleigh, Sevilla
McMahon, Francis J
Schmitt, Andrea
Falkai, Peter
Hasan, Alkomiet
Cacchiarelli, Davide
Dannlowski, Udo
Nenadić, Igor
Kircher, Tilo
Scheuss, Volker
Eder, Matthias
Binder, Elisabeth B
Spengler, Dietmar
Rossner, Moritz J
Ziller, Michael J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2912891934
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2912891934
Other Identifiers
ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2024.01.09.574815
