Neuronal polyunsaturated fatty acids are protective in FTD/ALS
Neuronal polyunsaturated fatty acids are protective in FTD/ALS
About this item
Full title
Author / Creator
Giblin, Ashling , Cammack, Alexander J , Blomberg, Niek , Mikheenko, Alla , Carcole, Mireia , Coneys, Rachel , Zhou, Lele , Yassene Mohammed , Olivier-Jimenez, Damien , Atilano, Magda L , Niccoli, Teresa , Coyne, Alyssa N , Van Der Kant, Rik , Lashley, Tammaryn , Giera, Martin , Partridge, Linda and Isaacs, Adrian M
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
We report a conserved transcriptomic signature of reduced fatty acid and lipid metabolism gene expression in human post-mortem ALS spinal cord and a Drosophila model of the most common genetic cause of FTD/ALS, a repeat expansion in C9orf72. To investigate lipid alterations, we performed lipidomics on C9FTD/ALS iPSC-neurons and post-mortem FTLD bra...
Alternative Titles
Full title
Neuronal polyunsaturated fatty acids are protective in FTD/ALS
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2915794501
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2915794501
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2024.01.16.575677
How to access this item
https://www.proquest.com/docview/2915794501?pq-origsite=primo&accountid=13902
