HMOX1 silencing prevents doxorubicin-induced cardiomyocyte injury, mitochondrial dysfunction, and fe...
HMOX1 silencing prevents doxorubicin-induced cardiomyocyte injury, mitochondrial dysfunction, and ferroptosis by downregulating CTGF
About this item
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Author / Creator
Qian, Jia , Wan, Wenting and Fan, Min
Publisher
Singapore: Springer Nature Singapore
Journal title
Language
English
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Publication information
Publisher
Singapore: Springer Nature Singapore
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Scope and Contents
Contents
Objectives
Doxorubicin is a type of effective antitumor drug but can contribute to cardiomyocyte injuries. We aimed to dissect the mechanism of the HMOX1/CTGF axis in DOX-induced cardiomyocyte injury, mitochondrial dysfunction, and ferroptosis.
Methods
Bioinformatics analysis was conducted to retrieve differentially expressed genes in a DO...
Alternative Titles
Full title
HMOX1 silencing prevents doxorubicin-induced cardiomyocyte injury, mitochondrial dysfunction, and ferroptosis by downregulating CTGF
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Record Identifier
TN_cdi_proquest_journals_2918743981
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2918743981
Other Identifiers
ISSN
1863-6705
E-ISSN
1863-6713
DOI
10.1007/s11748-022-01867-7