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HMOX1 silencing prevents doxorubicin-induced cardiomyocyte injury, mitochondrial dysfunction, and fe...

HMOX1 silencing prevents doxorubicin-induced cardiomyocyte injury, mitochondrial dysfunction, and fe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2918743981

HMOX1 silencing prevents doxorubicin-induced cardiomyocyte injury, mitochondrial dysfunction, and ferroptosis by downregulating CTGF

About this item

Full title

HMOX1 silencing prevents doxorubicin-induced cardiomyocyte injury, mitochondrial dysfunction, and ferroptosis by downregulating CTGF

Author / Creator

Publisher

Singapore: Springer Nature Singapore

Journal title

General thoracic and cardiovascular surgery, 2023-05, Vol.71 (5), p.280-290

Language

English

Formats

Publication information

Publisher

Singapore: Springer Nature Singapore

More information

Scope and Contents

Contents

Objectives
Doxorubicin is a type of effective antitumor drug but can contribute to cardiomyocyte injuries. We aimed to dissect the mechanism of the HMOX1/CTGF axis in DOX-induced cardiomyocyte injury, mitochondrial dysfunction, and ferroptosis.
Methods
Bioinformatics analysis was conducted to retrieve differentially expressed genes in a DO...

Alternative Titles

Full title

HMOX1 silencing prevents doxorubicin-induced cardiomyocyte injury, mitochondrial dysfunction, and ferroptosis by downregulating CTGF

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2918743981

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2918743981

Other Identifiers

ISSN

1863-6705

E-ISSN

1863-6713

DOI

10.1007/s11748-022-01867-7

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