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Challenging the Astral mass analyzer - going beyond 5200 proteins per single-cell at unseen quantita...

Challenging the Astral mass analyzer - going beyond 5200 proteins per single-cell at unseen quantita...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2920890471

Challenging the Astral mass analyzer - going beyond 5200 proteins per single-cell at unseen quantitative accuracy to study cellular heterogeneity

About this item

Full title

Challenging the Astral mass analyzer - going beyond 5200 proteins per single-cell at unseen quantitative accuracy to study cellular heterogeneity

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2024-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

A detailed proteome map is crucial for understanding molecular pathways and protein functions. Despite significant advancements in sample preparation, instrumentation, and data analysis, single-cell proteomics is currently limited by proteomic depth and quantitative performance. We combine a zero dead-end volume chromatographic column running at hi...

Alternative Titles

Full title

Challenging the Astral mass analyzer - going beyond 5200 proteins per single-cell at unseen quantitative accuracy to study cellular heterogeneity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2920890471

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2920890471

Other Identifiers

DOI

10.1101/2024.02.01.578358