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Protein interaction map of APOBEC3 enzyme family reveals deamination-independent role in cellular fu...

Protein interaction map of APOBEC3 enzyme family reveals deamination-independent role in cellular fu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2922686067

Protein interaction map of APOBEC3 enzyme family reveals deamination-independent role in cellular function

About this item

Full title

Protein interaction map of APOBEC3 enzyme family reveals deamination-independent role in cellular function

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2024-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Human APOBEC3 enzymes are a family of single-stranded (ss)DNA and RNA cytidine deaminases that act as part of the intrinsic immunity against viruses and retroelements. These enzymes deaminate cytosine to form uracil which can functionally inactivate or cause degradation of viral or retroelement genomes. In addition, APOBEC3s have deamination indepe...

Alternative Titles

Full title

Protein interaction map of APOBEC3 enzyme family reveals deamination-independent role in cellular function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2922686067

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2922686067

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2024.02.06.579137