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Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genet...

Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genet...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2925282261

Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia

About this item

Full title

Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2024-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Frontotemporal dementia (FTD) is the most common cause of early-onset dementia with 10-20% of cases caused by mutations in one of three genes: GRN, C9orf72, or MAPT. To effectively develop therapeutics for FTD, the identification and characterization of biomarkers to understand disease pathogenesis and evaluate the impact of specific therapeutic st...

Alternative Titles

Full title

Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2925282261

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2925282261

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2024.02.09.579529