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Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease...

Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2925283721

Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Despite recent advances in understanding disease biology, treatment of Group 3/4 medulloblastoma remains a therapeutic challenge in pediatric neuro-oncology. Bulk-omics approaches have identified considerable intertumoral heterogeneity in Group 3/4 medulloblastoma, including the presence of clear single-gene oncogenic drivers in only a subset of ca...

Alternative Titles

Full title

Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2925283721

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2925283721

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2024.02.09.579690