CDKN1B (p27kip1) enhances drug tolerant persister CTCs by restricting polyploidy following mitotic i...
CDKN1B (p27kip1) enhances drug tolerant persister CTCs by restricting polyploidy following mitotic inhibitors
About this item
Full title
Author / Creator
Horwitz, Elad , Taronish Dorab Dubash , Szabolcs, Anna , Wittner, Ben S , Kreuzer, Johannes , Morris, Robert , Bardia, Aditya , Chirn, Brian , Wiley, Devon , Che, Dante , Russel, Hunter C , Herrera Lopez, Xcanda I , Fox, Douglas B , Antmen, Ezgi , Ting, David T , Haas, Wilhelm , Sade-Feldman, Moshe , Maheswaran, Shyamala and Haber, Daniel A
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
The mitotic inhibitor docetaxel (DTX) is often used to treat endocrine-refractory metastatic breast cancer, but initial responses are mitigated as patients eventually have disease progression. Using a cohort of ex vivo cultures of circulating tumor cells (CTCs) from patients with heavily pretreated breast cancer (n=18), we find two distinct pattern...
Alternative Titles
Full title
CDKN1B (p27kip1) enhances drug tolerant persister CTCs by restricting polyploidy following mitotic inhibitors
Authors, Artists and Contributors
Author / Creator
Taronish Dorab Dubash
Szabolcs, Anna
Wittner, Ben S
Kreuzer, Johannes
Morris, Robert
Bardia, Aditya
Chirn, Brian
Wiley, Devon
Che, Dante
Russel, Hunter C
Herrera Lopez, Xcanda I
Fox, Douglas B
Antmen, Ezgi
Ting, David T
Haas, Wilhelm
Sade-Feldman, Moshe
Maheswaran, Shyamala
Haber, Daniel A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2930089290
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2930089290
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2024.02.20.581202
How to access this item
https://www.proquest.com/docview/2930089290?pq-origsite=primo&accountid=13902
