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A highly scalable approach to topic modelling in single-cell data by approximate pseudobulk projecti...

A highly scalable approach to topic modelling in single-cell data by approximate pseudobulk projecti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2931022068

A highly scalable approach to topic modelling in single-cell data by approximate pseudobulk projection

About this item

Full title

A highly scalable approach to topic modelling in single-cell data by approximate pseudobulk projection

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2024-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Probabilistic topic modelling has become essential in many types of single-cell data analysis. Based on probabilistic topic assignments in each cell, we identify the latent representation of cellular states, and topic-specific gene frequency vectors provide interpretable bases to be compared with known cell-type-specific marker genes. However, fitt...

Alternative Titles

Full title

A highly scalable approach to topic modelling in single-cell data by approximate pseudobulk projection

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2931022068

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2931022068

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2024.02.21.581497