Escape from X inactivation is directly modulated by levels of Xist non-coding RNA
Escape from X inactivation is directly modulated by levels of Xist non-coding RNA
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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In placental females, one copy of the two X chromosomes is largely silenced during a narrow developmental time window, in a process mediated by the non-coding RNA Xist. Here, we demonstrate that Xist can initiate X-chromosome inactivation (XCI) well beyond early embryogenesis. By modifying its endogenous level, we show that Xist has the capacity to...
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Full title
Escape from X inactivation is directly modulated by levels of Xist non-coding RNA
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TN_cdi_proquest_journals_2931189178
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2931189178
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E-ISSN
2692-8205
DOI
10.1101/2024.02.22.581559
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https://www.proquest.com/docview/2931189178?pq-origsite=primo&accountid=13902
