Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Edit...
Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing
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United States: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
United States: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Natural killer (NK) cells' unique ability to kill transformed cells expressing stress ligands or lacking major histocompatibility complexes (MHC) has prompted their development for immunotherapy. However, NK cells have demonstrated only moderate responses against cancer in clinical trials and likely require advanced genome engineering to reach thei...
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Full title
Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing
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TN_cdi_proquest_journals_2951255865
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2951255865
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ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2024.03.05.582637