RNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and...
RNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer
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Liu, Xiaoyi , Wei, Qinglv , Yang, Chenyue , Zhao, Hongyan , Xu, Jie , Mobet, Youchaou , Luo, Qingya , Yang, Dan , Zuo, Xinzhao , Chen, Ningxuan , Yang, Yu , Li, Li , Wang, Wei , Yu, Jianhua , Xu, Jing , Liu, Tao and Yi, Ping
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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5-Methylcytosine (m
5
C) is a common RNA modification that modulates gene expression at the posttranscriptional level, but the crosstalk between m
5
C RNA modification and biomolecule condensation, as well as transcription factor-mediated transcriptional regulation, in ovarian cancer, is poorly understood. In this study, we revealed tha...
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RNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer
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TN_cdi_proquest_journals_3028036544
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3028036544
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ISSN
2092-6413,1226-3613
E-ISSN
2092-6413
DOI
10.1038/s12276-024-01184-4