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Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior

Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3052307909

Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior

About this item

Full title

Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior

Publisher

London: Nature Publishing Group UK

Journal title

Molecular psychiatry, 2024-01, Vol.29 (1), p.57-73

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The Wnt/β-catenin pathway contains multiple high-confidence risk genes that are linked to neurodevelopmental disorders, including autism spectrum disorder. However, its ubiquitous roles across brain cell types and developmental stages have made it challenging to define its impact on neural circuit development and behavior. Here, we show that TCF7L2...

Alternative Titles

Full title

Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3052307909

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3052307909

Other Identifiers

ISSN

1359-4184,1476-5578

E-ISSN

1476-5578

DOI

10.1038/s41380-023-02281-y

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