Phase 1 study of safety and preliminary efficacy of intranasal transplantation of human neural stem...
Phase 1 study of safety and preliminary efficacy of intranasal transplantation of human neural stem cells (ANGE-S003) in Parkinson’s disease
About this item
Full title
Author / Creator
Jiang, Shenzhong , Wang, Han , Yang, Chengxian , Feng, Feng , Xu, Dan , Zhang, Mengyu , Xie, Manqing , Cui, Ruixue , Zhu, Zhaohui , Jia, Chenhao , Liu, Linwen , Wang, Lin , Yang, Xunzhe , Yang, Yingmai , Hao, Honglin , Liu, Zhaoxi , Wu, Zhihong , Leng, Ling , Li, Xiaoxin , Sun, Xicai , Zhao, Xiongfei , Xu, Jinfang , Zhang, Yi , Wan, Xinhua , Bao, Xinjie and Wang, Renzhi
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd
Subjects
More information
Scope and Contents
Contents
BackgroundIntranasal transplantation of ANGE-S003 human neural stem cells showed therapeutic effects and were safe in preclinical models of Parkinson’s disease (PD). We investigated the safety and tolerability of this treatment in patients with PD and whether these effects would be apparent in a clinical trial.MethodsThis was a 12-month, single-cen...
Alternative Titles
Full title
Phase 1 study of safety and preliminary efficacy of intranasal transplantation of human neural stem cells (ANGE-S003) in Parkinson’s disease
Authors, Artists and Contributors
Author / Creator
Wang, Han
Yang, Chengxian
Feng, Feng
Xu, Dan
Zhang, Mengyu
Xie, Manqing
Cui, Ruixue
Zhu, Zhaohui
Jia, Chenhao
Liu, Linwen
Wang, Lin
Yang, Xunzhe
Yang, Yingmai
Hao, Honglin
Liu, Zhaoxi
Wu, Zhihong
Leng, Ling
Li, Xiaoxin
Sun, Xicai
Zhao, Xiongfei
Xu, Jinfang
Zhang, Yi
Wan, Xinhua
Bao, Xinjie
Wang, Renzhi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_3052639140
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3052639140
Other Identifiers
ISSN
0022-3050,1468-330X
E-ISSN
1468-330X
DOI
10.1136/jnnp-2023-332921
