Hypoxia-inducible factor 3α1 increases epithelial-to-mesenchymal transition and iron uptake to drive...
Hypoxia-inducible factor 3α1 increases epithelial-to-mesenchymal transition and iron uptake to drive colorectal cancer liver metastasis
About this item
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Background/objectives
Hypoxia-inducible factor (HIF)-3α1’s role in colorectal cancer (CRC) cells, especially its effects on epithelial-mesenchymal transition (EMT), zinc finger E-box binding homeobox 2 (ZEB2) gene expression, and iron metabolism, remains largely unstudied. This research sought to elucidate these relationships.
Methods
RNA-...
Alternative Titles
Full title
Hypoxia-inducible factor 3α1 increases epithelial-to-mesenchymal transition and iron uptake to drive colorectal cancer liver metastasis
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Record Identifier
TN_cdi_proquest_journals_3068991449
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3068991449
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ISSN
0007-0920,1532-1827
E-ISSN
1532-1827
DOI
10.1038/s41416-024-02699-3
