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Therapeutic potential of vitamin D3 in mitigating high glucose‑induced renal damage: Mechanistic ins...

Therapeutic potential of vitamin D3 in mitigating high glucose‑induced renal damage: Mechanistic ins...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3069031322

Therapeutic potential of vitamin D3 in mitigating high glucose‑induced renal damage: Mechanistic insights into oxidative stress inhibition and TXNIP/NLRP3 signaling pathway blockade

About this item

Full title

Therapeutic potential of vitamin D3 in mitigating high glucose‑induced renal damage: Mechanistic insights into oxidative stress inhibition and TXNIP/NLRP3 signaling pathway blockade

Publisher

Athens: Spandidos Publications

Journal title

Experimental and therapeutic medicine, 2024-07, Vol.28 (1), Article 277

Language

English

Formats

Publication information

Publisher

Athens: Spandidos Publications

More information

Scope and Contents

Contents

In the development of diabetic nephropathy, pathological damage such as interstitial fibrosis and cell apoptosis often occur in renal tubules. In the present study, diabetic and control group mice were randomly treated with vitamin D3 or vehicle for 6 months. In addition, human renal tubular epithelial (HK-2) cells were cultured in high-glucose med...

Alternative Titles

Full title

Therapeutic potential of vitamin D3 in mitigating high glucose‑induced renal damage: Mechanistic insights into oxidative stress inhibition and TXNIP/NLRP3 signaling pathway blockade

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3069031322

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3069031322

Other Identifiers

ISSN

1792-0981

E-ISSN

1792-1015

DOI

10.3892/etm.2024.12565

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