POS0791 INHIBITION OF THE GLUCOSE TRANSPORTER GLUT1 WEAKENS CHONDROCYTES AND AGGRAVATES MURINE OSTEO...
POS0791 INHIBITION OF THE GLUCOSE TRANSPORTER GLUT1 WEAKENS CHONDROCYTES AND AGGRAVATES MURINE OSTEOARTHRITIS
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Author / Creator
Latourte, A. , Carrabin, S. , Slitine, I. , Bouchemla, Z. , Ea, H.K. , Cohen Solal, M. , Richette, P. and Hay, E.
Publisher
Kidlington: Elsevier Limited
Journal title
Language
English
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Publisher
Kidlington: Elsevier Limited
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Contents
Background:Articular cartilage is an avascular tissue with limited oxygen supply. In a hypoxic environment, the metabolism of chondrocytes therefore relies mainly on glycolysis, which depends on the supply of glucose by membrane transporters. GLUT1 is the most abundantly expressed glucose transporter in chondrocytes.Objectives:In this study, we exa...
Alternative Titles
Full title
POS0791 INHIBITION OF THE GLUCOSE TRANSPORTER GLUT1 WEAKENS CHONDROCYTES AND AGGRAVATES MURINE OSTEOARTHRITIS
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Record Identifier
TN_cdi_proquest_journals_3086388438
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3086388438
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2024-eular.3872
