Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inn...
Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells
About this item
Full title
Author / Creator
Publisher
United States: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
United States: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Hearing loss is the most common form of sensory deficit. It occurs predominantly due to hair cell (HC) loss. Mammalian HCs are terminally differentiated by birth, making HC loss challenging to replace. Here, we show the pharmacogenetic downregulation of
, a tight junction protein, generates robust supernumerary inner HCs (IHCs) in mice. The ecto...
Alternative Titles
Full title
Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_3126180761
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3126180761
Other Identifiers
ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2023.10.08.561387
