CTCF depletion decouples enhancer-mediated gene activation from chromatin hub formation during cellu...
CTCF depletion decouples enhancer-mediated gene activation from chromatin hub formation during cellular differentiation
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Enhancers and promoters interact in 3D chromatin structures to regulate gene expression. Here, we characterize the mechanisms that drive the formation of these structures and their function in gene regulation in a lymphoid-to-myeloid transdifferentiation system. Based on analyses at base-pair resolution, we demonstrate a close correlation between b...
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Full title
CTCF depletion decouples enhancer-mediated gene activation from chromatin hub formation during cellular differentiation
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TN_cdi_proquest_journals_3131626289
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3131626289
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E-ISSN
2692-8205
DOI
10.1101/2024.11.20.624447
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https://www.proquest.com/docview/3131626289?pq-origsite=primo&accountid=13902
