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Drug combinations targeting FAK and MEK overcomes tumour heterogeneity in glioblastoma

Drug combinations targeting FAK and MEK overcomes tumour heterogeneity in glioblastoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3134571097

Drug combinations targeting FAK and MEK overcomes tumour heterogeneity in glioblastoma

About this item

Full title

Drug combinations targeting FAK and MEK overcomes tumour heterogeneity in glioblastoma

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2024-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Glioblastoma (GBM) is an aggressive brain tumour with limited treatment options and poor prognosis, largely due to its heterogeneity and the involvement of multiple intracellular signalling pathways that contribute to drug resistance. Standard therapies have not significantly improved patient outcomes over the past two decades. While recent advance...

Alternative Titles

Full title

Drug combinations targeting FAK and MEK overcomes tumour heterogeneity in glioblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3134571097

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3134571097

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2024.11.26.625442