mRNArchitect: optimized design of mRNA sequences
mRNArchitect: optimized design of mRNA sequences
About this item
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
mRNA design is the critical first step in the development of a new vaccine or therapy. The mRNA primary sequence is assembled from multiple elements, including the coding sequence of the target protein or gene, flanking untranslated regions that enhance translation, and the poly(A) tail, which improves mRNA stability. The coding sequence can also b...
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Full title
mRNArchitect: optimized design of mRNA sequences
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TN_cdi_proquest_journals_3140665182
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3140665182
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DOI
10.1101/2024.12.03.626696
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https://www.proquest.com/docview/3140665182?pq-origsite=primo&accountid=13902
