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Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis

Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3147176191

Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis

About this item

Full title

Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis

Publisher

Ann Arbor: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2024-11, Vol.134 (22), p.1-17

Language

English

Formats

Publication information

Publisher

Ann Arbor: American Society for Clinical Investigation

More information

Scope and Contents

Contents

A major limitation of immunotherapy is the development of resistance resulting from cancer-mediated inhibition of host lymphocytes. Cancer cells release CCL2 to recruit classical monocytes expressing its receptor CCR2 for the promotion of metastasis and resistance to immunosurveillance. In the circulation, some CCR2-expressing classical monocytes l...

Alternative Titles

Full title

Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3147176191

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3147176191

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI179527.

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