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Molecular architecture of human dermal sleeping nociceptors

Molecular architecture of human dermal sleeping nociceptors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3147576784

Molecular architecture of human dermal sleeping nociceptors

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Human dermal sleeping nociceptors display ongoing activity in neuropathic pain, affecting 10% of the population. Despite advances in rodents, a molecular marker for these mechano-insensitive C-fibers (CMis) in human skin remains elusive, preventing targeted therapy. In this translational Patch-seq study, we combine single-cell transcriptomics follo...

Alternative Titles

Full title

Molecular architecture of human dermal sleeping nociceptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3147576784

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3147576784

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2024.12.20.629638