Mitochondrial damage triggers therapy-induced senescence
Mitochondrial damage triggers therapy-induced senescence
About this item
Full title
Author / Creator
Baltira, Chrysiida , Alkan, Ferhat , Mayayo-Peralta, Isabel , Miriam Guillén Navarro , Thijssen, Bram , Lempers, Rose , Pello, Kimberley , Fedorushkova, Daria M , Their, Anna , Jochems, Fleur , Rozing, Kicky , Bleijerveld, Onno , Janssen, Hans , Kuil, Laura E , Beijnen, Jos H , Faller, William J , Silva, Joana , Bernards, Rene , Olaf Van Tellingen and De Gooijer, Mark C
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
Glioblastoma (GBM) is a fatal brain tumor with a critical need for better therapies. It is known that the PI3K, MAPK, and CDK4/6 signaling pathways are hyper-activated in these tumors; however, previous studies have used very high concentration of inhibitors to assess their importance, with mixed results. Here we developed PMCi, a combination appro...
Alternative Titles
Full title
Mitochondrial damage triggers therapy-induced senescence
Authors, Artists and Contributors
Author / Creator
Alkan, Ferhat
Mayayo-Peralta, Isabel
Miriam Guillén Navarro
Thijssen, Bram
Lempers, Rose
Pello, Kimberley
Fedorushkova, Daria M
Their, Anna
Jochems, Fleur
Rozing, Kicky
Bleijerveld, Onno
Janssen, Hans
Kuil, Laura E
Beijnen, Jos H
Faller, William J
Silva, Joana
Bernards, Rene
Olaf Van Tellingen
De Gooijer, Mark C
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_3147786971
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3147786971
Other Identifiers
DOI
10.1101/2024.12.20.629667
How to access this item
https://www.proquest.com/docview/3147786971?pq-origsite=primo&accountid=13902
