Early-life Oxytocin Rescues Hippocampal Synaptic Plasticity and Episodic Memory in a Mouse Model of...
Early-life Oxytocin Rescues Hippocampal Synaptic Plasticity and Episodic Memory in a Mouse Model of Fragile X Syndrome
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Cognitive disabilities including impairments to episodic memory are debilitating features of autism spectrum disorder (ASD). Here we report that early-life treatment with oxytocin (OXT) fully restores episodic memory and associated synaptic plasticity in a rodent model of an ASD. Fmr1-knockout (KO) mice -- which mimic the single gene mutation in Fr...
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Early-life Oxytocin Rescues Hippocampal Synaptic Plasticity and Episodic Memory in a Mouse Model of Fragile X Syndrome
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TN_cdi_proquest_journals_3147787221
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3147787221
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E-ISSN
2692-8205
DOI
10.1101/2024.12.20.629802
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https://www.proquest.com/docview/3147787221?pq-origsite=primo&accountid=13902
