Molecular phenotypes of critical illness confer prognostic and biological enrichment in sub-Saharan...
Molecular phenotypes of critical illness confer prognostic and biological enrichment in sub-Saharan Africa: a prospective cohort study from Uganda
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Author / Creator
Cummings, Matthew J , Lutwama, Julius J , Tomoiaga, Alin S , Owor, Nicholas , Lu, Xuan , Ross, Jesse E , Muwanga, Moses , Nsereko, Christopher , Nayiga, Irene , Nie, Kai , Kayiwa, John , Che, Xiaoyu , Wayengera, Misaki , Kim-Schulze, Seunghee , Lipkin, W Ian , O’Donnell, Max R and Bakamutumaho, Barnabas
Publisher
England: BMJ Publishing Group Ltd and British Thoracic Society
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English
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Publisher
England: BMJ Publishing Group Ltd and British Thoracic Society
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Contents
The generalisability of critical illness molecular phenotypes to low- and middle-income countries (LMICs) is unknown. We show that molecular phenotypes derived in high-income countries (hyperinflammatory and hypoinflammatory, reactive and uninflamed) stratify sepsis patients in Uganda by physiological severity, mortality risk and dysregulation of k...
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Full title
Molecular phenotypes of critical illness confer prognostic and biological enrichment in sub-Saharan Africa: a prospective cohort study from Uganda
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TN_cdi_proquest_journals_3149104224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3149104224
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ISSN
0040-6376,1468-3296
E-ISSN
1468-3296
DOI
10.1136/thorax-2024-222412