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Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b l...

Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b l...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3149312129

Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b locus depends on tissue-specific epigenetic context

About this item

Full title

Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b locus depends on tissue-specific epigenetic context

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2024-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Topologically associated domains (TADs) are believed to be involved in the regulation of gene expression. While the impact of TAD perturbations is usually studied in developmental genes with highly cell-type-specific expression patterns, this study examines genes with broad expression profiles divided by a strong insulatory boundary. We focused on...

Alternative Titles

Full title

Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b locus depends on tissue-specific epigenetic context

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3149312129

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3149312129

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2024.08.16.608309