A framework integrating multiscale in-silico modeling and experimental data predicts CD33 CAR-NK cyt...
A framework integrating multiscale in-silico modeling and experimental data predicts CD33 CAR-NK cytotoxicity across target cell types
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Uncovering mechanisms and predicting tumor cell responses to CAR-NK cytotoxicity is essential for improving therapeutic efficacy. Currently, the complexity of these effector-target interactions and the donor-to-donor variations in NK cell receptor (NKR) repertoire require functional assays to be performed experimentally for each manufactured CAR-NK...
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Full title
A framework integrating multiscale in-silico modeling and experimental data predicts CD33 CAR-NK cytotoxicity across target cell types
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TN_cdi_proquest_journals_3150948608
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3150948608
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E-ISSN
2692-8205
DOI
10.1101/2024.12.31.630941
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https://www.proquest.com/docview/3150948608?pq-origsite=primo&accountid=13902
