Selection of pre-leukemic hematopoietic stem cells driven by distinct extracellular matrix molecules
Selection of pre-leukemic hematopoietic stem cells driven by distinct extracellular matrix molecules
About this item
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Author / Creator
Jassinskaja, Maria , Bode, Daniel , Gonka, Monika , Roumeliotis, Theodoros I , Hogg, Alexander J , Rubio Lara, Juan A , Bennett, Ellie , Milek, Joanna , Theeuwes, Bart , Vijayabaskar, M S , Lilia Cabrera Cosme , Che, James L C , Macdonald, Sandy , Ahmed, Sophia , Hall, Benjamin A , Vasey, Grace , Kooi, Helena , Belmonte, Miriam , Shepherd, Mairi S , Brackenbury, William J , Kucinski, Iwo , Yamazaki, Satoshi , Holding, Andrew N , Cull, Alyssa H , Wilson, Nicola K , Gottgens, Berthold , Chaudhary, Jyoti S and Kent, David G
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Despite rapid advances in mapping genetic drivers and gene expression changes in hematopoietic stem cells (HSCs), there is a relative paucity of studies at the protein level. Here, we perform a deep, multi-omic characterization (epigenome, transcriptome and proteome) of HSCs carrying a loss-of-function mutation in Tet2, a key driver of increased se...
Alternative Titles
Full title
Selection of pre-leukemic hematopoietic stem cells driven by distinct extracellular matrix molecules
Authors, Artists and Contributors
Author / Creator
Bode, Daniel
Gonka, Monika
Roumeliotis, Theodoros I
Hogg, Alexander J
Rubio Lara, Juan A
Bennett, Ellie
Milek, Joanna
Theeuwes, Bart
Vijayabaskar, M S
Lilia Cabrera Cosme
Che, James L C
Macdonald, Sandy
Ahmed, Sophia
Hall, Benjamin A
Vasey, Grace
Kooi, Helena
Belmonte, Miriam
Shepherd, Mairi S
Brackenbury, William J
Kucinski, Iwo
Yamazaki, Satoshi
Holding, Andrew N
Cull, Alyssa H
Wilson, Nicola K
Gottgens, Berthold
Chaudhary, Jyoti S
Kent, David G
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_3158241520
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3158241520
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E-ISSN
2692-8205
DOI
10.1101/2025.01.20.633881
How to access this item
https://www.proquest.com/docview/3158241520?pq-origsite=primo&accountid=13902