Durable reconstitution of sinonasal epithelium by transplant of CFTR gene corrected airway stem cell...
Durable reconstitution of sinonasal epithelium by transplant of CFTR gene corrected airway stem cells
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Author / Creator
Bravo, Dawn T , Vaidyanathan, Sriram , Baker, Jeannette , Sinha, Vrishti , Tsai, Esmond , Roozdar, Pooya , Kong, William W , Atkinson, Patrick J , Patel, Zara M , Hwang, Peter H , Rao, Vidya K , Negrin, Robert S , Wine, Jeffrey J , Milla, Carlos , Sellers, Zachary M , Desai, Tushar J , Porteus, Matthew H and Nayak, Jayakar V
Publisher
United States: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publisher
United States: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Modulator agents that restore cystic fibrosis transmembrane conductance regulator (CFTR) function have revolutionized outcomes in cystic fibrosis, an incurable multisystem disease. Barriers exist to modulator use, making local CFTR gene and cell therapies attractive, especially in the respiratory tract. We used CRISPR to gene-correct CFTR in upper...
Alternative Titles
Full title
Durable reconstitution of sinonasal epithelium by transplant of CFTR gene corrected airway stem cells
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Record Identifier
TN_cdi_proquest_journals_3159906436
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3159906436
Other Identifiers
ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2025.01.24.634776
