The 9p21.3 coronary artery disease risk locus drives vascular smooth muscle cells to an osteochondro...
The 9p21.3 coronary artery disease risk locus drives vascular smooth muscle cells to an osteochondrogenic state
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Publisher
United States: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
United States: Cold Spring Harbor Laboratory Press
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Contents
Genome-wide association studies have identified common genetic variants at ~300 human genomic loci linked to coronary artery disease (CAD) susceptibility. Among these genomic regions, the most impactful is the 9p21.3 CAD risk locus, which spans a 60 kb gene desert and encompasses ~80 SNPs in high linkage disequilibrium. Despite nearly two decades s...
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Full title
The 9p21.3 coronary artery disease risk locus drives vascular smooth muscle cells to an osteochondrogenic state
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TN_cdi_proquest_journals_3165216027
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3165216027
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ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2024.05.25.595888
