Spatial transcriptomics uncovers hybrid, pro-inflammatory and pro-fibrotic cellular niches in pulmon...
Spatial transcriptomics uncovers hybrid, pro-inflammatory and pro-fibrotic cellular niches in pulmonary granuloma of patients with chronic sarcoidosis
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Author / Creator
Leonard, Christian , Yilmaz, Hande , Ruwisch, Jannik , Giercke, Leon , Seeliger, Benjamin , Jan-Christopher Kamp , Bayraktar, Sirvan , Ewen, Raphael , Graalmann, Theresa , Fuge, Jan , Greer, Mark , Ius, Fabio , Welte, Tobias , Hohlfeld, Jens M , Hoeper, Marius M , Gottlieb, Jens , Kaminski, Naftali , Prasse, Antje , Jonigk, Danny , Yang, Li , Falk, Christine , Neubert, Lavinia and Schupp, Jonas Christian
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Background: Sarcoidosis is a disease of unknown etiology characterized by the formation of immune cell accumulation (granuloma) in the lung and other tissues. Chronic sarcoidosis may lead to pulmonary fibrosis. Aim: To unravel cellular niches within pulmonary granuloma of chronic sarcoidosis patients using spatial transcriptomics. Methods: Spatial...
Alternative Titles
Full title
Spatial transcriptomics uncovers hybrid, pro-inflammatory and pro-fibrotic cellular niches in pulmonary granuloma of patients with chronic sarcoidosis
Authors, Artists and Contributors
Author / Creator
Yilmaz, Hande
Ruwisch, Jannik
Giercke, Leon
Seeliger, Benjamin
Jan-Christopher Kamp
Bayraktar, Sirvan
Ewen, Raphael
Graalmann, Theresa
Fuge, Jan
Greer, Mark
Ius, Fabio
Welte, Tobias
Hohlfeld, Jens M
Hoeper, Marius M
Gottlieb, Jens
Kaminski, Naftali
Prasse, Antje
Jonigk, Danny
Yang, Li
Falk, Christine
Neubert, Lavinia
Schupp, Jonas Christian
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_3165948512
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3165948512
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E-ISSN
2692-8205
DOI
10.1101/2025.02.11.636632
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https://www.proquest.com/docview/3165948512?pq-origsite=primo&accountid=13902