Natural Genetic Variation in Yeast Reveals That NEDD4 Is a Conserved Modifier of Mutant Polyglutamin...
Natural Genetic Variation in Yeast Reveals That NEDD4 Is a Conserved Modifier of Mutant Polyglutamine Aggregation
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United States: Oxford University Press
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English
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United States: Oxford University Press
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Abstract
A feature common to late onset proteinopathic disorders is an accumulation of toxic protein conformers and aggregates in affected tissues. In the search for potential drug targets, many studies used high-throughput screens to find genes that modify the cytotoxicity of misfolded proteins. A complement to this approach is to focus on stra...
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Natural Genetic Variation in Yeast Reveals That NEDD4 Is a Conserved Modifier of Mutant Polyglutamine Aggregation
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TN_cdi_proquest_journals_3169761214
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3169761214
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ISSN
2160-1836
E-ISSN
2160-1836
DOI
10.1534/g3.118.200289
