Drosophila Larval Brain Neoplasms Present Tumour-Type Dependent Genome Instability
Drosophila Larval Brain Neoplasms Present Tumour-Type Dependent Genome Instability
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England: Oxford University Press
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Language
English
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England: Oxford University Press
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Abstract
Single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) are found at different rates in human cancer. To determine if these genetic lesions appear in Drosophila tumors we have sequenced the genomes of 17 malignant neoplasms caused by mutations in l(3)mbt, brat, aurA, or lgl. We have found CNVs and SNPs in all the tumors....
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Full title
Drosophila Larval Brain Neoplasms Present Tumour-Type Dependent Genome Instability
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TN_cdi_proquest_journals_3169763413
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3169763413
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ISSN
2160-1836
E-ISSN
2160-1836
DOI
10.1534/g3.117.300489
