Genome-wide Methylation Profiling in Crohn's Disease Identifies Altered Epigenetic Regulation of Key...
Genome-wide Methylation Profiling in Crohn's Disease Identifies Altered Epigenetic Regulation of Key Host Defense Mechanisms Including the Th17 Pathway
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Oxford, UK: Oxford University Press
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English
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Oxford, UK: Oxford University Press
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BackgroundGermline variation in the 71 Crohn's disease (CD) loci implicated by genome-wide association studies (GWAS) only accounts for approximately 25% of estimated heritability. The contribution of epigenetic alterations to disease pathogenesis is emerging as a research priority.Materials and Methods:The methylation status of 27,578 CpG sites ac...
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Genome-wide Methylation Profiling in Crohn's Disease Identifies Altered Epigenetic Regulation of Key Host Defense Mechanisms Including the Th17 Pathway
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TN_cdi_proquest_journals_3169783851
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3169783851
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1078-0998
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1536-4844
DOI
10.1002/ibd.21912
