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Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925

Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3169860311

Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925

About this item

Full title

Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925

Publisher

Cambridge, UK: Cambridge University Press

Journal title

The international journal of neuropsychopharmacology, 2010-04, Vol.13 (3), p.273-287

Language

English

Formats

Publication information

Publisher

Cambridge, UK: Cambridge University Press

More information

Scope and Contents

Contents

Dopamine D3 receptors are preferentially localized in the limbic system and midbrain, and thus may be involved in the pathophysiology of neuropsychiatry disorders. [11C](+)-PHNO is the first preferential D3 receptor radioligand in humans, yet there are no blockade studies with a D3 receptor antagonist in humans. This study characterized the blockad...

Alternative Titles

Full title

Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3169860311

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3169860311

Other Identifiers

ISSN

1461-1457

E-ISSN

1469-5111

DOI

10.1017/S1461145709990642

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