P-286 Notch Signaling and TNF-α Synergistically Up-regulate Stem Cell-Specific Genes, OLFM4 and UBD,...
P-286 Notch Signaling and TNF-α Synergistically Up-regulate Stem Cell-Specific Genes, OLFM4 and UBD, in the Inflamed Intestinal Epithelia of IBD Patients
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Oxford, UK: Oxford University Press
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English
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Oxford, UK: Oxford University Press
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The intestinal epithelium of inflammatory bowel disease (IBD) patients is exposed to various pro-inflammatory cytokines, the most important of which is TNF-α. We have previously shown that the Notch signaling pathway is also up-regulated in the intestinal epithelial cells (IECs) of such mucosa, and contributes to IEC proliferation and mucosal regen...
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Full title
P-286 Notch Signaling and TNF-α Synergistically Up-regulate Stem Cell-Specific Genes, OLFM4 and UBD, in the Inflamed Intestinal Epithelia of IBD Patients
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TN_cdi_proquest_journals_3169868990
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3169868990
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ISSN
1078-0998
E-ISSN
1536-4844
DOI
10.1097/01.MIB.0000512827.36560.28
