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The Role of GC-Biased Gene Conversion in Shaping the Fastest Evolving Regions of the Human Genome

The Role of GC-Biased Gene Conversion in Shaping the Fastest Evolving Regions of the Human Genome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3171248522

The Role of GC-Biased Gene Conversion in Shaping the Fastest Evolving Regions of the Human Genome

About this item

Full title

The Role of GC-Biased Gene Conversion in Shaping the Fastest Evolving Regions of the Human Genome

Publisher

United States: Oxford University Press

Journal title

Molecular biology and evolution, 2012-03, Vol.29 (3), p.1047-1057

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

GC-biased gene conversion (gBGC) is a recombination-associated evolutionary process that accelerates the fixation of guanine or cytosine alleles, regardless of their effects on fitness. gBGC can increase the overall rate of substitutions, a hallmark of positive selection. Many fast-evolving genes and noncoding sequences in the human genome have GC-...

Alternative Titles

Full title

The Role of GC-Biased Gene Conversion in Shaping the Fastest Evolving Regions of the Human Genome

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3171248522

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3171248522

Other Identifiers

ISSN

0737-4038

E-ISSN

1537-1719

DOI

10.1093/molbev/msr279

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