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Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotop...

Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotop...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3195389829

Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotopic mouse model of hepatocellular carcinoma

About this item

Full title

Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotopic mouse model of hepatocellular carcinoma

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer Immunology, Immunotherapy, 2019-12, Vol.68 (12), p.1959-1969

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Hepatic stellate cells (HSCs) are important stromal cells and pivotal mediators involved in the pathogenesis and immunosuppression of hepatocellular carcinoma (HCC). The liver has been demonstrated to be a site for accumulation of tumor-induced myeloid-derived suppressor cells (MDSCs). We previously reported that HSCs induced an increase in the num...

Alternative Titles

Full title

Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotopic mouse model of hepatocellular carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3195389829

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3195389829

Other Identifiers

ISSN

0340-7004,1432-0851

E-ISSN

1432-0851

DOI

10.1007/s00262-019-02414-9

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